Eficacia de las células estromales mesenquimales (MSC) como tratamiento para pacientes con enfermedad obstructiva crónica (EPOC): Revisión Sistemática
Resumen
Objetivo: Determinar la eficacia del tratamiento con células estromales mesenquimales (MSC), en pacientes con enfermedad pulmonar obstructiva crónica (EPOC). Materiales y métodos: Análisis descriptivo, corte transversal, orientado hacia una revisión sistemática de artículos en inglés, publicados durante los últimos 6 años, en bases de datos como: PubMed, ScienceDirect, ClinicalTrials.gov; a través del uso de descriptores (DeCS) y operadores booleanos como: “Mesenchymal Stromal Cells¨ AND ¨Therapy¨ AND ¨COPD¨. Resultados: Se determinó que las MSC son prometedoras para aplicaciones terapéuticas en EPOC, dada la facilidad para obtenerlas, su escasa inmunogenicidad, sus propiedades reparadoras tisulares e inmunomodulación. Conclusiones: El éxito de esta terapia a las semanas o meses de la terapia con MSC, van a depender de la fase de la enfermedad, la presencia de exacerbaciones y factores de riesgo asociados a cada paciente.
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Derechos de autor 2023 Erika Pamela Abad Molina, Sonia Azucena Ortiz Reinoso, Juan Antonio Coyago Iñiguez, Fernando Mauricio León Martínez
Esta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0.
